Bioprocess Services

When you step through our doors, you take a giant step toward turning your biotech idea into a success. With your direction and our no-nonsense approach, you’ll be supported by the experts, private lab space and cutting edge equipment you need to go through all the necessary stages of scale-up and commercialization.

Lab Scale Bioprocess

  • Five 7.5L bioreactors available for bioprocess development, scale-up parameter optimization, and tech transfer. Fully automated process control and fed-batch capable. Full and secure data capture.

  • Analytical lab for in-process and final sample analysis including gas chromatography, ultra-performance liquid chromatography, microscopy, spectrophotometry, stock culture storage, laminar flow hoods, incubators & shakers, and more.

Download Equipment Sheet
Photo of Dakota BioWorx bioprocess engineer working in lab.
Photo of Dakota BioWorx bioprocess engineer standing in front of 300L bioreactor.

Bioprocess Scale Up

  • Two 7.5L, two 40L, one 75L, and two 300L bioreactors available for scale-up development and tech transfer in advance of piloting.

  • Isolated bioprocessing laboratories for focused scale-up development at each reactor scale.

  • Access to full analytical assays and laboratory equipment for scale-up development support.

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Fermentation Pilot Plant

  • 3,000L bioreactor for pilot-scale production, optimization, and proof of scalability demonstrations.

  • Access to smaller-scale bioreactors for seed-train development and analytical equipment for in-process sample and final product characterization.

  • Flexible pilot-plant design with multiple utility drops for for additional unit-operations and process equipment installations.

Download Equipment Sheet
Photo of Dakota BioWorx's 3000L Eppendorf bioreactor.
Photo of Dakota BioWorx employee opening the Relco Spray Dryer.

Downstream Processing

  • Continuous centrifugation via disk-stack or decanter methods for processing between 300-3000L of fermentation broth.

  • Tangential-flow-filtration (TFF) via ceramic membranes allows concentration of target molecules.

  • Spray drying capabilities provide a final dried product powder at production scale.

Download Equipment Sheet

Ready to get started? Schedule a free consultation with our team.

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